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Render: the No Spin PRP processing syringe at rest in its positioning clamp after settling, with a plasma layer above the red cells
No Spin PRP® System

PRP, without the spin.

Platelet-rich plasma, separated at normal gravity in a single-use kit. No centrifuge.

Watch the film 0:59 How it works

Investigational device. Not cleared or approved by the U.S. FDA and not available for sale.

Gravity only
1 g
Hands-free settling
≈30 min
Centrifuges or power
0
Single-use
1 kit
How it works

Two physical effects. No centrifuge.

A proprietary polymer solution stacks red cells into rouleaux. A 30° tilt lets them settle fast while plasma rises along the upper wall.

The science in detail
Illustration: red blood cells stacked into rouleaux among smaller platelets

Red cells stack into rouleaux

A premixed proprietary polymer solution promotes red-cell aggregation. The stacks settle much faster than single cells.

Diagram: in a tube tilted 30 degrees, red cells slide down the lower wall while plasma streams up the upper wall

The Boycott effect

Tip up at about 30°, red cells fall a short distance to the lower wall and slide down it.

Render: close-up of the processing syringe after settling, a golden plasma layer above the red cells

An upper plasma layer forms

The plasma is transferred to a second syringe through a Luer connector, leaving the red cells behind.

Development footage

Watch it settle.

Development footage of an earlier 50 mL prototype at normal gravity: red cells settle and an upper plasma layer forms. Time-lapse.

Visual appearance alone does not establish platelet count, function, or sterility.

Time-lapse
Transcript
  1. Platelet-rich plasma is used in knee and back injections, eye drops, wound care, hair restoration and facial rejuvenation.
  2. But making it takes a centrifuge.
  3. That means costly equipment, trained staff, and open transfers that risk contamination.
  4. And every spin damages platelets: once activated, they release their growth factors, and they're spent.
  5. No Spin PRP takes out the centrifuge.
  6. Draw blood into the syringe with our proprietary polymer solution.
  7. Set it at an angle. The red cells settle on their own.
  8. In about thirty minutes, platelet-rich plasma is ready, right at the point of care.
  9. Several kits can settle side by side, hands-free.
  10. The No Spin PRP System is an investigational device, not cleared or approved by the FDA.
Render: the No Spin PRP kit in its tray: processing syringe, excipient vial, positioning clamp, needle, cap, connector, and butterfly set
The kit

One single-use kit.

Everything that touches the blood is single-use.

  • Premixed excipient (proprietary polymer solution)
  • 30 mL Luer-lock processing syringe
  • Excipient draw needle
  • Butterfly venipuncture set
  • Luer-lock syringe cap
  • Female-to-female Luer connector
  • Plastic positioning clamp
  • Labels and instructions

Working configuration under development. A second sterile 20 mL syringe, supplied by the user, collects the plasma.

Proposed use

Preparation of autologous platelet-rich plasma at the point of care for mixing with autograft and/or allograft bone before application to a bony defect, to improve handling characteristics.

Proposed intended use, under development. Current planned research is ex vivo; study PRP and graft are not administered to participants.

What development studies will evaluate

  1. 01

    PRP composition

    Cell counts, platelet concentration, and pH of the prepared plasma.

  2. 02

    Platelet function

    Activation state and responsiveness of platelets after preparation.

  3. 03

    Bone-graft handling

    How PRP–graft mixtures handle compared with appropriate controls.

Justin Karlin, MD, MS, founder and CEO of OcuSera
Company

Built in Los Angeles.

OcuSera, Inc. was founded in 2023 by Justin Karlin, MD, MS, an ophthalmologist and oculofacial plastic surgeon with more than 55 peer-reviewed publications.

About OcuSera

Research, clinical, and investor inquiries.

We welcome conversations with researchers, clinicians, and investors interested in centrifuge-free PRP preparation.

Contact OcuSera